Disodium Hydrogen Phosphate Dodecahydrate

Disodium Hydrogen Phosphate Dodecahydrate
Disodium hydrogen phosphate is an important class of phosphate compounds, and its family members are distinguished primarily by the amount of water of crystallization. The following is a comparison of its major members and their properties:
1. Disodium Hydrogen Phosphate Dodecahydrate (CAS 7558-79-4)
Characteristics: White crystalline powder, no water of crystallization, chemically stable.
Melting point: 243-245°C
Solubility: soluble in water (solubility about 56.5% at 20℃), aqueous solution is weakly alkaline (pH 8.8-9.2); insoluble in ethanol.
Density: 1.064 g/mL (20℃).
Application: ①Industry: acidity buffer for boiler water treatment, fireproofing agent for printing and dyeing industry, fabric weight gainer. ② Food: as pH adjuster, bulking agent, used in meat processing to maintain moisture. ③Pharmaceuticals: used as pharmaceutical excipient and buffer.
2. Disodium phosphate dodecahydrate (Na₂HPO₄-12H₂O)
Characteristics: white crystal or granular powder, containing 12 water of crystallization, easy to weather and lose water of crystallization.
Stability: gradually lose water of crystallization in air, can be completely dehydrated to form anhydrous material at high temperature (100℃).
Solubility: soluble in water, alkalinity of the solution is weaker than that of anhydrous material (pH≈9.0).
Application: Commonly used in laboratory buffer solution preparation, food preservatives, etc.
3. Other
Disodium hydrogen phosphate dihydrate (Na₂HPO₄-2H₂O):
It tends to lose some of its water of crystallization at room temperature to form heptahydrate or anhydrous15.
Disodium hydrogen phosphate heptahydrate (Na₂HPO₄-7H₂O):
Commonly used as an industrial intermediate, melts and loses water of crystallization when heated to 35.1°C
Among them, Disodium Hydrogen Phosphate Dodecahydrate (CAS 7558-79-4) is mainly prepared by spray drying method, neutralization method and complex decomposition method. Dust masks and protective glasses are required to avoid dust inhalation or skin contact. In addition, Disodium Hydrogen Phosphate Dodecahydrate needs to be stored in a cool and dry environment, avoiding coexistence with acidic substances (e.g. ammonium nitrate) to prevent deliquescence or chemical reaction.
Disodium Hydrogen Phosphate Dodecahydrate family members have their own characteristics in terms of stability, solubility and application scenarios due to differences in water of crystallization content. Among them, Disodium Hydrogen Phosphate Dodecahydrate is the core choice for industrial and pharmaceutical applications due to its high stability and versatility.
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